District 110 is one of 11 member districts across southwestern Minnesota that is served by SouthWest Metro Intermediate District 288 (formerly the Southwest Metro Educational Cooperative). SouthWest Metro provides programs in special education, career and technical education, adult basic education, and alternative education.

An intermediate district is a specialty school district that provides defined student services to a group of regular member school district. SouthWest Metro is one of four intermediate school districts in the state, which combined serve more than 20,000 students each year in the areas of special education, area learning centers, career technical programs, and online learning.